I am happy to announce that my paper entitled "Enhancing Intercellular Coordination: Rewiring Quorum Sensing Networks for Increased Protein Expression through Autonomous Induction" is now available online. In this paper, my co-authors and I create a genetically engineered bacterium with advanced quorum sensing kinetics. These cells produce their own coordination molecules and then rapidly uptake these molecules, which trigger protein expression. This enhanced uptake increases the coordination among the bacteria, resulting in increased protein expression. As induction molecules for protein expression are cost-prohibitive at industrial scale, we envision these kinds of systems will prove beneficial in metabolic engineering applications.
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Amin ZargarBS Chemical Engineering Archives
June 2017
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